The Nnamdi Azikiwe University Teaching Hospital, Nnewi was established by Anambra State of Nigeria (ASN) Edict No 10 of 1988 as Anambra State University of Technology Teaching Hospital Nnewi, and shared premises with the then General Hospital, Nnewi.
The General Hospital was officially handed over to the Teaching Hospital Management Board on the 16th June, 1990. Following the handover, a number of essential hospital equipments were either refurbished or renovated.
The Hospital was officially commissioned on Friday 19th July, 1991 by the then Anambra State Military Governor; Col.Robert Akonobi and the General Hospital were taken over as a temporary site. The Federal Government of Nigeria through Decree No 68 of 1992 then renamed the Hospital of Nnamdi Azikiwe University Teaching Hospital in honor of the late saga and foremost politician, Rt. Hon. Dr. Nnamdi Azikiwe GGFR.PC Owelle of Onitsha.