General Manager - Pharmaceutical at Adexen

Job Introduction

• Adexen is recruiting a General Manager for a pharmaceutical manufacturer in Nigeria to establish and lead its oral and topical pharmaceuticals business, from project delivery to commercial operations.

Responsibilities
The General Manager will deliver new manufacturing projects, lead technology transfer and product development, and take the facility through commissioning, regulatory approval and commercial launch. Once operational, the role will own plant performance, business growth and profitability.

• Establish the business unit, develop its business plan, prioritise products and manufacturing lines, and build the technical and operational team.
• Oversee facility design, equipment selection, installation, commissioning and qualification.
• Manage suppliers, contractors and technical partners to deliver manufacturing projects within approved scope, budgets and timelines.
• Identify product opportunities and technical partners, overseeing formulation development, analytical method transfer, scale-up and process validation.
• Lead technology transfer and bring new products and manufacturing lines into commercial operation.
• Take priority products through registration, regulatory approval and commercial launch in collaboration with Quality, Regulatory Affairs and commercial teams.
• Lead manufacturing operations covering tablets, capsules, powders, syrups, suspensions, creams and ointments.
• Oversee granulation, compression, capsule filling and coating capabilities, together with dedicated oral liquid and topical semi-solid production lines.
• Manage production performance, yields, manufacturing costs and supply reliability.
• Maintain GMP compliance, appropriate facility segregation, cross-contamination controls and inspection readiness.
• Work with Quality and Regulatory Affairs to secure and maintain NAFDAC approvals.
• Own the business unit’s budget and profit and loss, ensuring effective cost control and profitable growth.
• Coordinate pricing, demand planning, distribution and product launches with the Group’s commercial team.
• Report project progress, operational results and financial performance to the Group Managing Director.

Desired Skills and Experience:

• Hands-on commercial-scale pharmaceutical manufacturing experience across multiple dosage forms, including oral solids and either oral liquids or topical semi-solids.
• Experience in both beta-lactam and non-beta-lactam production, with a strong understanding of facility segregation and cross-contamination controls.
• Proven track record of transferring and manufacturing specialty drugs.
• Demonstrated experience bringing new manufacturing lines and pharmaceutical products into commercial operation.
• Strong technical knowledge of formulation development, analytical method transfer, scale-up, commissioning, qualification and process validation.
• Ability to lead GMP-compliant manufacturing operations and work effectively with Quality and Regulatory Affairs on approvals and inspection readiness.
• Strong project management capabilities, including supplier coordination, budget management and delivery against timelines.
• Business leadership capabilities covering profit and loss, manufacturing performance, team development and collaboration with commercial functions.